FIND ARTICLE

TH17 LYMPHOCYTES A NEW ALLY IN THE FIGHT AGAINST OVARIAN CANCER?

Th17 are a newly discovered population of T helper lymphocytes characterized by the production of IL-17 (IL-17A). Interleukin 17 activates production of cytokines which are responsible for migration of neutrophils and development of inflammatory reaction. Among the other cytokines secreted by Th17 cells are TNF-a, IL-1b, IL-6 and IL-22. Development of Th17 lymphocytes gave rise numerous researches on mechanisms leading to differentiation of CD4+ cells towards new subpopulation and enabled to define factors conditioning the line.

Molecular basis of menstrual bleeding

During puberty the endometrium undergoes cyclic changes morphologically defined as a phase of growth, secretion, and exfoliation. They occur as a result of periodically recurring changes in the activity of the hypothalamic-pituitary-ovary, which results in fluctuations in the concentration of estrogen and progesterone in the blood. The sexual cycle, where there has been no fertilization of the ovum, the corpus luteum hormone action expires, decreased serum estradiol and progesterone in the blood, in consequence of which comes to shedding of the endometrium and menstrual bleeding.

The Editorial Board
Andrzej Łukaszyk - przewodniczący, Zofia Bielańska-Osuchowska, Szczepan Biliński, Mieczysław Chorąży, Aleksander Koj, Włodzimierz Korochoda, Leszek Kuźnicki, Aleksandra Stojałowska, Lech Wojtczak

Editorial address:
Katedra i Zakład Histologii i Embriologii Uniwersytetu Medycznego w Poznaniu, ul. Święcickiego 6, 60-781 Poznań, tel. +48 61 8546453, fax. +48 61 8546440, email: mnowicki@ump.edu.pl

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