The use of somatic cells in the mammalian cloning

Although somatic cloning efficiency of not more than 1? Animals born 2% relative to the number of reconstructed oocytes, the cloning is used to obtain transgenic animals producing milk or urine of human therapeutic proteins to rescue dying breeds and species of mammals, and even restitution of species already extinct. Work is underway aiming to achieve? by somatic cloning? organs for xenotransplantation as well as differentiated cells presenting cell therapy for the perspective of many diseases.

Primary human embryonic cells obtained from embryonic blastocysts nodes and a few weeks fetuses. Confirmed their ability to hold more than one year in culture in vitro in undifferentiated state . It was also shown that after transplantation in vivo in mice and in vitro , they can differentiate into tissues derived from all three germ layers . Thanks to these properties, primary human cells carrying a hope for therapeutic applications .