GPR7 and GPR8 (G-protein-coupled Receptors) are two recently discovered and structural- ly related orphan receptors linked to protein G. They are present both in central nervous system and in peripheral organs. Recently, endogenous ligands of these receptors have been identified. One of them is a 29 amino acid residues long, uniquely modified with bromine and, thus, termed the neuropeptide B (NPB). The other, neuropeptide W (NPW), has been identified in two molecular forms of, respectively, 23 and 30 amino acids (NPW23 and NPW30).

Cerebellin biosynthesis, the presence and the role of

Cerebellin is a relatively new and little-known neuropeptide, built of 16 amino acids. It is now known about the existence of four precursor proteins termed precerebeliny. Within a single species for each precerebellins genes located on different chromosomes, but in each case consist of three exons. Comparison between precerebellins between different species reveals their very high homology.

Beacon - biologically active peptide associated with the occurrence of obesity

Beacon (BC ) is a newly discovered peptide isolated from the hypothalamus piaskówki ( Psammomys obesus) , which has been implicated in the regulation of energy balance. It is also known under the names of ubiquitin -like protein 5 ( UBL5 ) and homologous to ubiquitin ( Hub 1 ) . His presence is observed in almost all tissues examined . Beacon gene is highly conserved interspecies . Its expression in the hypothalamus, is proportional to glucose and insulin levels and body fat percentage and body mass in an animal species Psammomys obesus .

The Editorial Board
Andrzej Łukaszyk - przewodniczący, Zofia Bielańska-Osuchowska, Szczepan Biliński, Mieczysław Chorąży, Aleksander Koj, Włodzimierz Korochoda, Leszek Kuźnicki, Aleksandra Stojałowska, Lech Wojtczak

Editorial address:
Katedra i Zakład Histologii i Embriologii Uniwersytetu Medycznego w Poznaniu, ul. Święcickiego 6, 60-781 Poznań, tel. +48 61 8546453, fax. +48 61 8546440, email:

PBK Postępby biologi komórki