Vascular endothelium and the blood cells are derived from mesodermal cells of the common hemangioblastu. The confirmation of the close relationship of both cell lines are common antigens, occurring in the early stages of differentiation. Endothelial precursor cells, defined as CD34 + CD133 + Flk-1 +, can be differentiated in vitro cultured endothelial cells. Progenitors of endothelial cells, isolated from bone marrow, cord blood and peripheral blood in vivo may incorporate into the vessel wall and damaged endothelial function to take. Mastering techniques for the isolation and propagation of these cells causing potential use in the therapy of diseases which require repairing blood vessels, especially myocardial infarction. Further knowledge of the mechanisms governing neoangiogenesis may also allow you to control the growth of tumors.