Alzheimer's disease is one of the most widespread neurodegenerative disorder. The etiology of this disease is not completely elucidated. Amyloid plaques (extracellular aggregates of amyloid β peptides Aβ) and neurofibrillary tangles (intracellular deposits of hyperphosphorylated tau protein) are histopa- thological hallmarks of the Alzheimer disease. These morphological changes are present mostly in brain regions involved in cognition, emotion, learning and memory. The critical events in the pathogenesis of Alzheimer's disease are caused by amyloid β peptides.