Dendritic cells (DC ) are the most important antigen-presenting cells (APCs ) to T lymphocytes ripeness DC cells is crucial for the type of T cell response Immature DC induces cell tolerance state , while the mature cell DC - a full immune response. This is very important in transplantation , and in particular of graft rejection reactions after organ transplantation . DC donor cell presents the antigen in a direct way , whereas DC recipient cell in an indirect way . DC cells are immature or tolerogenic properties may prolong allograft survival .