Duchenne muscular dystrophy is one of the most frequent and most serious types of muscular dystrophies. Both molecular aspects and efficient methods of DMD therapy are not known yet. C. elegans is a promising experimental model in the research on DMD. The paper demonstrates important similarities between structure and function of C. elegans and human muscle cells, which enable a more precise analysis of the muscle degeneration process. The role of ion channels EGL-19 and BK-SLO in muscle degeneration in C. elegans was indicated.