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Cytokines are proteins regulating the development and duration of normal and pathological immune response. They are responsible for the transduction of informations among immune system cells and are involved in the communication between the immune and neuroendocrine systems. Cytokines play roles in the immune response, hematopoiesis, apoptosis, inflammation and homeostasis. Distinct lymphocyte populations are characterized by the spectrum of synthesized cytokines and their production may be altered in diseases. Analysis of cytokines expression may be helpful in the evaluation of functional status of the immune system. Flow cytometry is the method of choice for the analysis of single cells. Antigens can be detected with specific fluorochrome-labeled antibodies on the cell surface and within the cells, after fixation and permeabilization of the cell membrane. This method offers a wide range of research possibilities, but also creates problems.
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The Editorial Board
Andrzej Łukaszyk - przewodniczący, Zofia Bielańska-Osuchowska, Szczepan Biliński, Mieczysław Chorąży, Aleksander Koj, Włodzimierz Korochoda, Leszek Kuźnicki, Aleksandra Stojałowska, Lech Wojtczak

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