The interest in the influence of drugs on the immune system , with special attention to opiates , according to the Increment is currently the number of addicts and patients stosujšcych morphine to relieve pain . Morphine acts differently on the immune system , hamujšc or nasilajšc response efficiency . Opiates Mogs affect the immune system indirectly bšdź Hanging with classical opioid receptors in the central nervous system , causing increased secretion of catecholamines and glucocorticoids , bšdź Mogs hanging directly with a specific opioid receptor - m3 located on leukocytes .